Guangzhou is in charge of round nematodiasis and study and obtain the new development

Guangzhou is in charge of round nematodiasis and study and obtain the new development
It is reported (the intersection of reporter and Zheng dexterous) Prevailing Guangzhou in charge of round morbidity mechanism of nematodiasis know in break out many times by our country, and not generally acknowledged the healing solution. Subsidiary Beijing Friendship Hospital of Capital University of Medical Sciences has observed people and should infect the single nuclear cells (PBMC) of peripheral blood after being ill for the first time Cell factor change,find whether whether it is out-of-balance in factor in the cells on Th1/Th2 it is that Guangzhou in charge of nematodiasises round's lasting one of mechanism, A benzene reach thiazole fill rice in, loose, can treat disease this through regulate internal the intersection of cell and the intersection of factor and level not uniting, thus in order to announce the morbidity mechanism of this disease and make the clinical healing solution to offer the experiment foundation. Thesis of this research was published in U.S.A. " parasitology of experiment " a few days ago.It is introduced Guangzhou it in charge of round nematodiasises to be many to eat raw or half eat with a larva the intersection of fresh water and the intersection of spiral shell and meat raw, initiate. The larva depends on for a living the central nervous system behind invading the human body, symptom of causing the headache, skin to unusually feel etc.. Most patients can fully recover, the heavy one can leave sequela and even die. This disease mainly prevails in every island of Southeast Asia and the Pacific Ocean. In 2003, Ministry of Public Health classified it as our country and sent infectious disease newly.Under the guidance of overcast great professor Zhen of Friendship Hospital in Beijing, Master degree candidate tricky cases of gift employ the intersection of PCR and method observe, in charge of round acute one and convalescence, patient of nematodiasis, by 43 Guangzhou dynamically ' After treating) PBMC cell factor gene expression competence,find whether rise obviously issues of patient IL-4, IL-5 and IL-10,etc. Th2 cell the expressions of factors acute. Among them, it is the most obvious that IL-5 rises, play a leading role in the immunity is replied; And Th1 cell factor IL-2 and IFN - �� are expressed for being low, thus has led to the fact Th1/Th2 expresses out-of-balancely. Discover people infect Guangzhou in charge of round nematode the peripheral blood have a liking for acid cells, rise obviously after being ill further, and its variation tendency keeps the same with horizontal height of IL-5 gene expression, indicate it is IL-5 dependence that Guangzhou is in charge of the rising that the round nematodiasis patient has a liking for acid cells.
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